Harwell, Oxfordshire: Assemblon Ltd, the custom oligonucleotide synthesis and chemistry company founded by Professor Tom Brown, Dr Daniel Singleton and Dr Richard Cunningham, has completed its move into new laboratories in the Research Complex at Harwell Campus, little more than a year after the company was founded. The expansion significantly increases its synthesis and purification capacity in response to growing demand.

The new laboratories sit next to the Diamond Light Source, the UK’s national synchrotron. They have eight fume hoods, synthetic chemistry facilities, high-throughput DNA/RNA synthesis and HPLC purification platforms, with additional synthesisers being commissioned. Assemblon can now take on higher volumes while keeping the direct, chemist-led service its customers rely on.

Co-founder Dr Richard Cunningham said: “The move gives us room we didn’t have, and the kit to use it. Demand has grown quickly, particularly for heavily modified and conjugated oligos. What doesn’t change is how we work: customers will still deal directly with our nucleic acid chemistry and applications experts.”

Dr Daniel Singleton, co-founder, added: “We’re seeing strong interest from biotech, pharma and academic groups around the world. The expansion means we can say yes to more complex projects and high-throughput synthesis.”

Assemblon makes DNA, RNA and chemically modified oligonucleotides, covering diagnostic and therapeutic chemistries, including ASOs, SSOs, siRNAs, miRNAs, conjugates, duplexes and aptamers. Every product is identity-confirmed by UPLC-MS before release, and the company is certified to ISO 9001:2015. Assemblon also offers UPLC-MS analysis of oligonucleotides as a standalone service, including identity confirmation, purity assessment and duplex characterisation. Assemblon publishes regular technical articles on oligonucleotide chemistry, modification, purification and analysis at www.assemblon.co.uk.

Harwell Campus is home to more than 6,000 people across some 240 organisations, including Diamond, the Rosalind Franklin Institute and the Rutherford Appleton Laboratory.

Media contact: Dr Richard Cunningham, richard.cunningham@assemblon.co.uk

Research Complex at Harwell, Harwell Campus

UPLC-MS suite in the new laboratories

Some of the preparative HPLC systems in the new purification laboratory

High-throughput multi-column synthesis platform

About Assemblon
Assemblon Ltd is a custom oligonucleotide synthesis and R&D chemistry company founded on decades of nucleic acid chemistry and manufacturing experience. Based at Harwell Campus, Oxfordshire, it manufactures DNA, RNA and chemically modified oligonucleotides, including duplexes and conjugates, with UPLC-MS identity confirmation on every product. ISO 9001:2015 certified.
www.assemblon.co.uk | sales@assemblon.co.uk