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Tool

Extinction coefficient

Calculate ε at 260 nm and molecular weight for any DNA / RNA / chimeric sequence. Modified monomers are looked up against our internal monomer library.

Sequence (5' → 3')
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Use [brackets] for modifications, (parentheses) for backbone mods. Type plain DNA bases, select, and right-click them to convert them to RNA, LNA, 2′-OMe, or add backbone mods like phosphorothioate.